David Goldstein from Columbia University Medical Center explains how to turn the complex information within the human genome into insights that can lead to better medicines for patients.
All in Health
CRISPR in the clinic
We explore how CRISPR is being used to develop transformative gene therapies, and the ethical implications of genetically engineering humans.
Searching for genetic superheroes
The search for genetic superheroes started with a simple question with a complicated answer: not why do we get sick, but why do we stay well?
Ringo the Superdog: how rare genetic variations can lead to new treatments
How a super-powered pup is paving the way for new treatments for muscular dystrophy.
Jeff Schoenebeck: Building a boopable snoot
Genetics have a big part to play in building a boopable snoot, from long-nosed greyhounds to flat-faced pugs.
Patchwork of mutation - Raheleh Rahbari
Raheleh Rahbari from the Wellcome Sanger Institute explains why our bodies are patchworks of mutation, right from the very start of life, and the impact this has on ageing and diseases like cancer and dementia.
If I could turn back time - Andrew Steele
Andrew Steele, author of Ageless talks about the science of ageing and why your toothbrush might be more useful for preventing ageing than that fancy moisturiser.
How do mRNA vaccines work?
If you can make an mRNA and you can get it into a cell, then the ribosomes in that cell will make whatever protein that mRNA encodes. And it’s here that we move from the 1960s right up to today, and to the story of mRNA vaccines.
Hunting for Huntington's
The year is 1872. A young American doctor, George Huntington, has just started his career, following in the footsteps of his father and grandfather, who were general practitioners in the prosperous Hamptons area of New York. Graduating from Columbia University the year before, at the tender age of 21, George is keen to make an impression on the medical world.